Donor Tissue Counseling
Back to Back Ovarian Stimulation Shortens Treatment Duration Without Compromising Outcomes https://www.fertstert.org/article/S0015-0282(23)01619-9/fulltext
Back to back cycles of ovarian stimulation (2 weeks from first retrieval to next stimulation start) shorten treatment duration with similar treatment outcomes regardless of ovarian reserve.
Murugappan G, Sikder M, Minjarez D, Kim J, Pasternak M, Klatsky P, Tran N. Fertility and Sterility. 2023 Oct.
Use of Calcium Ionophore Oocyte Activation Post-ICSI Results in Higher Blastocyst Formation Rates https://www.fertstert.org/article/S0015-0282(23)00836-1/fulltext
Calcium ionophore, frequently referred to as calcium activation, can be applied in patients with a history of poor embryo development to increase the number of embryos developing to the blastocyst stage. For many patients who otherwise have a poor prognosis with IVF, that means more viable embryos to work with, and better odds of a healthy pregnancy.
Kim J, Vaccari S, Klatsky P, Tran N, Sikder M, Murugappan G, Pasternak M, Minjarez D. Fertility and Sterility. 2023 Oct.
Oocyte Competency is not Affected by Duration of Cryopreservation: https://pubmed.ncbi.nlm.nih.gov/39633145/
Over a 9 year study period, the duration of oocyte cryopreservation did not affect the number of blastocysts or chromosomally normal blastocysts obtained after oocyte thaw.
Murugappan G, Sikder M, Vaccari S, Minjarez D, Tran N, Kim J, Klatsky P. J Assist Reprod Genet. 2025 Feb.
Spring has created the Egg Freezing Calculator based on our published outcome data since 2016 to help you develop realistic expectations around egg freezing, and to estimate your chance of having a healthy baby with your frozen eggs.
It means the care you receive here is constantly being tested, refined, and shared with the broader medical community. Our physicians aren’t just practicing medicine — they’re actively shaping it. Meet our team
We hope so. Whether you’re navigating unexplained infertility, recurrent loss, PCOS, or just starting to explore your options — there’s likely something in this library that speaks to your situation. And if you have questions, we’re here to walk you through it. Book a consult
Spring is where complex cases come to be taken seriously. Our team has published research on some of the most challenging conditions in reproductive medicine — because we see them every day. Talk to us
As our physicians publish, we add it here. Several of the studies in this library were published in 2025 and 2026 — this is living, breathing science, not a static credential page.
Being an informed patient makes a real difference. We encourage you to bring questions to your appointments, ask about studies that feel relevant to you, and be an active part of your own care. We’re at our best when you are too. Book a consult
Absolutely. You don’t need to understand the methodology to understand what matters — which is that the people treating you care enough to keep asking hard questions and publishing honest answers. Book a consult